The groups of brain tumors that are not from the glial tissue include meningiomas, schwannomas, craniopharyngiomas, germ cell tumors, pituitary adenomas, and pineal region tumors. The most common primary brain tumors are gliomas, which are divided into several types: astrocytomas, oligodendrogliomas, and ependymomas. Because of this, metastatic tumors often present with more neuropsychiatric symptoms. There are two types of tumors: ones that are primary, originating from the brain tissue, and ones that metastasize to numerous locations throughout the brain. Brain tumors may be classified based on their histopathologic characteristics or anatomical location. Since psychiatric nomenclature and disease parameters change constantly, it is difficult to analyze this topic in a consistent manner.īrain tumors are relatively common with an annual incidence of 00 for primary brain tumors and 8.00 for metastatic brain tumors. The majority of large studies discussing brain neoplasms and psychiatric symptoms date back to the 1930’s. This article reviews the existing literature regarding the diagnosis and management of this clinically complex condition. Symptoms that suggest work-up with neuroimaging include: new-onset psychosis, mood/memory symptoms, occurrence of new or atypical symptoms, personality changes, and anorexia without body dysmorphic symptoms. Early diagnosis is critical for improved quality of life.
There are no double blind studies except for post-diagnosis/-surgery studies. Our literature search yielded case reports, case studies, and case series. Search terms included psychiatric manifestations/symptoms, brain tumors/neoplasms. Search engines used include PubMed, Ovid, Psych Info, MEDLINE, and MedScape. A comprehensive review of the literature was conducted regarding reports of brain tumors and psychiatric symptoms from 1956-2014. Symptoms may be misleading, complicating the clinical picture. They may present with mood symptoms, psychosis, memory problems, personality changes, anxiety, or anorexia. Infrequently, psychiatric symptoms may be the only manifestation of brain tumors.
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